Local antibiotic susceptibility patterns (antibiograms)

Capital, Coast and Hutt Valley district

Wairarapa district

Recommended adult doses for ‘optimised’ antibiotic dosing

Note: many of these agents may require adjustment with significant renal impairment. Seek ID or pharmacy advice if necessary.

Amoxicillin – 1g tds
Augmentin – use ‘boosted augmentin’ (Augmentin 625mg tds + amoxicillin 500mg tds)
Ciprofloxacin – 750mg bd
Co-trimoxazole – 1440mg bd or 960mg tds

Amoxicillin – 1g q6h (standard dose sufficient for ‘I’ when given IV). If patient septic or >100kg use 2g q6h.
Augmentin – 1.2g q8h (standard dose sufficient for ‘I’ when given IV). If patient septic or >100kg use ‘boosted IV augmentin’ (Augmentin 1.2g q8h + Amoxicillin 1g q8h)
Benzylpenicillin 2.4g q6h (if treating meningitis then increase to q4h)
Ceftazidime – 2g q8h
Cefepime – 2g q8h
Piperacillin-tazobactam (Tazocin) – 4.5g q6h

Topical treatment options for conjunctivitis

	Chloramphenicol	Fusidic Acid	Tobramycin	Ciprofloxacin
*Staph aureus*	Susceptible	Susceptible	Susceptible	Susceptible
*Haemophilus influenzae*	Susceptible	Resistant	+/-	Susceptible
*Strep pneumoniae*	Susceptible	Resistant	Resistant	+/-
*Moraxella catarrhalis*	Susceptible	Resistant	Resistant	Susceptible
*Corynebacterium macginleyi*	Susceptible	Resistant	Resistant	Susceptible
*Pseudomonas aeruginosa*	Resistant	Resistant	Susceptible	Susceptible
Enterobacterales (e.g. E. coli, Klebsiella, Serratia)	Susceptible	Resistant	Susceptible	Susceptible

Antibiotic therapy